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Anti-MYC Polyclonal Antibody

產(chǎn)品簡介：

Anti-MYC Polyclonal Antibody
應(yīng)用 WB IHC
稀釋比例WB 1:2000-5000.IHC 1:50-200.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106458P

更新時間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

訪問量：1320

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產(chǎn)品介紹

Anti-MYC Polyclonal Antibody

英文名稱	Anti-MYC Polyclonal Antibody
宿主	Rabbit
別名	BHLHE39;c-Myc;MRTL;MYCC
應(yīng)用	WB IHC
稀釋比例	WB 1:2000-5000.IHC 1:50-200.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	63kDa
Gene ID	4609
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human MYC
性狀	液體
Public Immunogen Range	A synthetic peptide of human MYC
Swiss Prot	P01106
Subcellular Locations	Nucleus Cytoplasm
克隆類型	Polyclonal Antibody
背景資料	The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.