Anti-Delta4 Polyclonal Antibody
應用 WB
稀釋比例WB 1:3000.
交叉反應Human Mouse Rat

產(chǎn)品型號：K106504P

更新時間：2022-08-15

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Anti-Delta4 Polyclonal Antibody

英文名稱	Anti-Delta4 Polyclonal Antibody
宿主	Rabbit
別名	DLL4;AOS6;DLL 4;hdelta2;MGC126344
應用	WB
稀釋比例	WB 1:3000.
交叉反應	Human Mouse Rat
蛋白分子量	75kDa
Gene ID	54567
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human Delta4
性狀	液體
Public Immunogen Range	A synthetic peptide of human Delta4
Subcellular Locations	Cell membrane
Swiss Prot	Q9NR61
克隆類型	Polyclonal Antibody
背景資料	The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.