Anti-PGH2 Polyclonal Antibody
應(yīng)用 IHC
稀釋比例IHC 1:50-200.
交叉反應(yīng)Human

產(chǎn)品型號：K106634P

更新時間：2022-08-15

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Anti-PGH2 Polyclonal Antibody

英文名稱	Anti-PGH2 Polyclonal Antibody
宿主	Rabbit
別名	PTGS2;COX2;PHS II;PGHS-2
應(yīng)用	IHC
稀釋比例	IHC 1:50-200.
交叉反應(yīng)	Human
蛋白分子量	69kDa
Gene ID	5743
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human PGH2
性狀	液體
Public Immunogen Range	A synthetic peptide of human PGH2
Subcellular Locations	Cytoplasm
Swiss Prot	P35354
克隆類型	Polyclonal Antibody
背景資料	Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.