Anti-EGLN Polyclonal Antibody
應用 IHC
稀釋比例IHC 1:50-200.
交叉反應Human

產(chǎn)品型號：K106633P

更新時間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

訪問量：1040

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Anti-EGLN Polyclonal Antibody

英文名稱	Anti-EGLN Polyclonal Antibody
宿主	Rabbit
別名	ENG;END;CD105;Endoglin
應用	IHC
稀釋比例	IHC 1:50-200.
交叉反應	Human
蛋白分子量	71kDa
Gene ID	2022
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human EGLN
性狀	液體
Public Immunogen Range	A synthetic peptide of human EGLN
Subcellular Locations	Cytoplasm
Swiss Prot	P17813
克隆類型	Polyclonal Antibody
背景資料	Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors.